Characteristic of mTOR signaling and its involvement in the regulation of cell movements through remodeling the cytoskeleton architecture

• Date: 2015
• Main Authors: Kosach, V.R., Cherednyk, O.V., Khoruzhenko, A.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2015
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152428
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Characteristic of mTOR signaling and its involvement in the regulation of cell movements through remodeling the cytoskeleton architecture / V.R. Kosach, O.V. Cherednyk, A.I. Khoruzhenko // Biopolymers and Cell. — 2015. — Т. 31, № 1. — С. 5-14. — Бібліогр.: 50 назв. — англ.

mTOR kinase is one of the basic links at the crossroad of several signal transduction pathways. De­re­gulated mTOR kinase signaling accompanies the progress of cancer, diabetes, neurodegenerative disorders and aging. Implication of mTOR inhibitor rapamycin decreases migration and invasion of maligna...