Chromatin in fractal globule state: evidence from comet assay

• Published in: Вiopolymers and Cell
• Date: 2015
• Main Authors: Afanasieva, K.S., Chopei, M.I., Sivolob, A.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2015
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152439
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Chromatin in fractal globule state: evidence from comet assay / K.S. Afanasieva, M.I. Chopei, A.V. Sivolob // Вiopolymers and Cell. — 2015. — Т. 31, № 2. — С. 97-103. — Бібліогр.: 29 назв. — англ.

At higher order levels chromatin is organized into loops that appear as a result of contacts between distant loci. The aim of this work was to investigate the length distribution of the DNA loops in nucleoids obtained after lysis of either whole cells or isolated cell nuclei. Methods. We used single...