Cisplatin treatment of C6 rat glioma in vivo did not influence copy number alterations and growth pattern of tumor-derived resistant cells

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2015
• Hauptverfasser: Stepanenko, A.A., Baklaushev, V.P., Vassetzky, Y.S., Dmitrenko, V.V.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2015
• Schlagworte: Biomedicine
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152470
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Cisplatin treatment of C6 rat glioma in vivo did not influence copy number alterations and growth pattern of tumor-derived resistant cells / A.A. Stepanenko, V.P. Baklaushev, Y.S. Vassetzky, V.V. Dmitrenko // Вiopolymers and Cell. — 2015. — Т. 31, № 3. — С. 209-217. — Бібліогр.: 38 назв. — англ.

Aim. To investigate whether the cisplatin treatment of C6 rat glioma in vivo impacts the copy number alterations (CNAs), proliferation and colony formation efficiency (CFE) of tumor-derived cisplatin-resistant cells. Methods. The glioma modeling was performed by means of intracerebral stereotactic i...