MI1 – derivative of maleimide inhibits cell cycle progression in tumor cells of epithelial origin

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Garmanchuk, L.V., Denis, E.O., Nikulina, V.V., Dzhus, O.I., Skachkova, O.V., Ribalchenko, V.K., Ostapchenko, L.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152488
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: MI1 – derivative of maleimide inhibits cell cycle progression in tumor cells of epithelial origin / L.V. Garmanchuk, E.O. Denis, V.V. Nikulina, O.I. Dzhus, O.V. Skachkova, V.K. Ribalchenko, L.I. Ostapchenko // Вiopolymers and Cell. — 2013. — Т. 29, №. 1. — С. 70-74. — Бібліогр.: 14 назв. — англ.

Aim. MI1 is a promising maleimide derivative, which exhibits antiproliferative effect on different cells. The aim of present study was to investigate influence of MI1 on the cell cycle of cancer cells and its cytotoxity. Methods. The proliferative activity and viability of human cancer cell lines (c...