Model mass spectrometric study of competitive interactions of antimicrobial bisquaternary ammonium drugs and aspirin with membrane phospholipids

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2013
• Hauptverfasser: Pashynska, V.A., Kosevich, M.V., Gomory, A., Vekey, K.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2013
• Schlagworte: Molecular Biophysics
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152493
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Model mass spectrometric study of competitive interactions of antimicrobial bisquaternary ammonium drugs and aspirin with membrane phospholipids / V.A. Pashynska, M.V. Kosevich, A. Gomory, K. Vekey // Вiopolymers and Cell. — 2013. — Т. 29, №. 2. — С. 157-162. — Бібліогр.: 17 назв. — англ.

The aim of the study is to reveal molecular mechanisms of possible activity modulation of antimicrobial bis-quaternary ammonium compounds (BQAC) and aspirin (ASP) through noncovalent competitive complexation under their combined introduction into the model systems with membrane phospholipids. Method...