Stress factor – dependent differences in molecular mechanisms of premature cell senescence

• Published in: Вiopolymers and Cell
• Date: 2015
• Main Authors: Petrova, N.V., Velichko, A.K., Razin, S.V., Kantidze, O.L.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2015
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152588
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Stress factor – dependent differences in molecular mechanisms of premature cell senescence / N.V. Petrova, A.K. Velichko, N.V. Petrova, S.V. Razin, O.L. Kantidze // Вiopolymers and Cell. — 2015. — Т. 31, № 5. — С. 323-337. — Бібліогр.: 218 назв. — англ.

Cell senescence is an established cell stress response in the form of a permanent proliferation arrest accompanied by a complex phenotype. Senescent cells share several crucial features, such as lack of DNA synthesis, increased senescence-associated β-galactosidase activity and upregulation of cycli...