Glioma-associated protein CHI3L2 suppresses cells viability and induces G1/S transition arrest

• Published in: Вiopolymers and Cell
• Date: 2015
• ISSN: 0233-7657
• Main Authors: Avdieiev, S.S., Gera, L., Hodges, R., Dmytrenko, V.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2015
• Subjects: Short Communications
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152612
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Glioma-associated protein CHI3L2 suppresses cells viability and induces G1/S transition arrest / S.S. Avdieiev, L. Gera, R. Hodges, V.V. Dmytrenko // Вiopolymers and Cell. — 2015. — Т. 31, № 4. — С. 316-320. — Бібліогр.: 8 назв. — англ.

Aim. To analyze the effect of the CHI3L2 protein on malignant and non-malignant cell viability, and determined the CHI3L2 impact on the cell cycle and signaling pathways involved in the cell cycle regulation. Methods. MTT-based cell proliferation assay, FACS, western blot analysis. Results. The CHI3...