Apocynin attenuates motility and induces transition from sustained to transient EGF-dependent Akt activation in MCF-7 cells that overexpress adaptor protein Ruk/CIN85

• Published in: Вiopolymers and Cell
• Date: 2016
• Main Authors: Bazalii, A.V., Drobot, L.B., Komisarenko, S.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152748
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Apocynin attenuates motility and induces transition from sustained to transient EGF-dependent Akt activation in MCF-7 cells that overexpress adaptor protein Ruk/CIN85 / A.V. Bazalii, L.B. Drobot, S.V. Komisarenko // Вiopolymers and Cell. — 2016. — Т. 32, № 1. — С. 21-25. — Бібліогр.: 22 назв. — англ.

Aim. To study a possible involvement of NADPH oxidases in the control of cell motility and Akt signaling in the human breast adenocarcinoma MCF-7 cells that stably overexpress the full-length form of adaptor protein Ruk/CIN85. Methods. Cell motility was studied by a transwell migration assay. The dy...