Computational analysis of microarray gene expression profiles of lung cancer

• Published in: Вiopolymers and Cell
• Date: 2016
• Main Authors: Babichev, S.A., Kornelyuk, A.I., Lytvynenko, V.I., Osypenko, V.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Bioinformatics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152773
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Computational analysis of microarray gene expression profiles of lung cancer / S.A. Babichev, A.I. Kornelyuk, V.I. Lytvynenko, V.V. Osypenko // Вiopolymers and Cell. — 2016. — Т. 32, № 1. — С. 70-79. — Бібліогр.: 16 назв. — англ.

Aim. The article presents the researches on the optimization of the DNA microarray data processing, which is aimed at improving the quality of object clustering. Methods. Data preprocessing was performed with program R using Bioconductor package. Modelling the clustering process was made in the soft...