Lamina–associated chromatin in the context of the mammalian genome folding

• Published in: Вiopolymers and Cell
• Date: 2016
• Main Authors: Ulianov, S.V., Shevelyov, Y.Y., Razin, S.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152846
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Lamina–associated chromatin in the context of the mammalian genome folding / S.V. Ulianov, Y.Y. Shevelyov, S.V. Razin // Вiopolymers and Cell. — 2016. — Т. 32, № 5. — С. 327-333. — Бібліогр.: 41 назв. — англ.

Eukaryotic interphase chromatin is folded hierarchically. Mammalian chromosomes are partitioned into topo-logically associating domains (TADs) whose interactions with each other drive the spatial segregation of the bulk chromatin into A–compartment containing active genomic regions, and B–compartmen...