Transcriptome-based identification of PDGFA as a candidate secreted biomarker for hepatocellular carcinoma

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2016
• Hauptverfasser: Chesnokov, M.S., Krivtsova, O.M., Skovorodnikova, P.A., Makarova, A.S., Kustova, I.F., Logacheva, M.D., Penin, A.A., Klepikova, A.V., Shavochkina, D.A., Kudashkin, N.E., Moroz, E.A., Patyutko, Y.I., Kotelnikova, E.A., Lazarevich, N.L.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2016
• Schlagworte: Genomics, Transcriptomics and Proteomics
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152852
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Transcriptome-based identification of PDGFA as a candidate secreted biomarker for hepatocellular carcinoma / M.S. Chesnokov, O.M. Krivtsova, P.A. Skovorodnikova, A.S. Makarova, I.F. Kustova, M.D. Logacheva, A.A. Penin, A.V. Klepikova, D.A. Shavochkina, N.E. Kudashkin, E.A. Moroz, Y.I. Patyutko, E.A. Kotelnikova, N.L. Lazarevich // Вiopolymers and Cell. — 2016. — Т. 32, № 6. — С. 418-432. — Бібліогр.: 26 назв. — англ.

Aim. Identification of candidate secreted biomarkers for hepatocellular carcinoma (HCC) diagnosis. Methods. Genes upregulated in HCC tissue and encoding secreted proteins were identified by RNA-seq. Gene expression changes in HCC were evaluated by RT-qPCR and meta-analysis of public databases. Bioma...