Design of 4-(4-dialkylaminostyryl) -pyridinium dyes for fluorescent detection of amyloid fibrils

• Опубліковано в: : Вiopolymers and Cell
• Дата: 2016
• Автори: Inshyn, D.I., Chernii, S.V., Kovalska, V.B., Yarmoluk, S.M.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут молекулярної біології і генетики НАН України 2016
• Теми: Bioorganic Chemistry
• Онлайн доступ: https://nasplib.isofts.kiev.ua/handle/123456789/152855
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Design of 4-(4-dialkylaminostyryl) -pyridinium dyes for fluorescent detection of amyloid fibrils / D.I. Inshyn, S.V. Chernii, V.B. Kovalska, S.M. Yarmoluk // Вiopolymers and Cell. — 2016. — Т. 32, № 4. — С. 289-299. — Бібліогр.: 16 назв. — англ.

The pathological proteins aggregation into the fibrillar structures is common to a large group of amyloid-related disorders, such as neurodegenerative diseases. Accordingly, there is a need for development of analytical tools, particularly fluorescent probes for detection of amyloid fibrils. Aim. To...