The polymorphisms of genes involved in DNA methylation in patients with malignancies from West Ukraine

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2016
• Hauptverfasser: Dmytruk, I.M., Makukh, H.V., Thyrkus, M.Y., Kitsera, N.I.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2016
• Schlagworte: Biomedicine
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152856
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: The polymorphisms of genes involved in DNA methylation in patients with malignancies from West Ukraine / I.M. Dmytruk, H.V. Makukh, M.Y. Thyrkus, N.I. Kitsera // Вiopolymers and Cell. — 2016. — Т. 32, № 4. — С. 279-288. — Бібліогр.: 34 назв. — англ.

Aim. To determine a potential role of single-nucleotide polymorphisms in the genes involved in the DNA methylation process (MTHFR, MTR, TYMS) in the breast cancer risk and risk of leukemia in a case-control study from West Ukraine. Methods. Genotyping of MTHFR 677 C>T, MTR 2756 A>G and TS 3R2R...