Use of lectin as a vector molecule for delivery of medicinal products to cells and tissues

• Published in: Вiopolymers and Cell
• Date: 2016
• Main Authors: Antonyuk, V.O., Klyuchivska, O.Yu., Antonyuk, R.V., Lozynskyi, A.V., Pohranychna, Kh.R., Lesyk, R.B., Stoika, R.S.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152862
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Use of lectin as a vector molecule for delivery of medicinal products to cells and tissues / V.O. Antonyuk, O.Yu. Klyuchivska, R.V. Antonyuk, A.V. Lozynskyi, Kh.R. Pohranychna, R.B. Lesyk, R.S. Stoika // Вiopolymers and Cell. — 2016. — Т. 32, № 6. — С. 461-467. — Бібліогр.: 13 назв. — англ.

Aim. The conjugation of low-molecular compounds with antitumor activity to lectin and evaluation of the biological activity of the obtained conjugate. Methods. Organic synthesis; obtaining and analyzing Pisum sativum agglutinin with thiopyrano[2,3-d]thiazole derivative conjugate; its biological test...