Familial adenomatous polyposis: age of onset and association with mutations of the APC gene in patients from West Ukraine

• Published in: Вiopolymers and Cell
• Date: 2017
• Main Authors: Lozynska, M.R., Lozynskyy, Y.S., Plawski, A., Pinyazhko, R.O., Prokopchuk, N.M., Fedota, O.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Subjects: Biomedicine
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152908
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Familial adenomatous polyposis: age of onset and association with mutations of the APC gene in patients from West Ukraine / M.R. Lozynska, Y.S. Lozynskyy, A. Plawski, R.O. Pinyazhko, N.M. Prokopchuk, O.M. Fedota // Вiopolymers and Cell. — 2017. — Т. 33, № 2. — С. 102-115. — Бібліогр.: 46 назв. — англ.

Aim. To evaluate the average age of familial adenomatous polyposis (FAP) onset in both males, females and in their relatives, carriers or not carriers of the APC gene mutations, to estimate the anticipation in successive generations for early identification of the individuals in the risk group. Meth...