Antineoplastic activity of novel thiazole derivatives

• Published in: Вiopolymers and Cell
• Date: 2017
• Main Authors: Finiuk, N.S., Hreniuh, V.P., Ostapiuk, Yu.V., Matiychuk, V.S., Frolov, D.A., Obushak, M.D., Stoika, R.S., Babsky, A.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152919
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Antineoplastic activity of novel thiazole derivatives / N.S. Finiuk, V.P. Hreniuh, Yu.V. Ostapiuk, V.S. Matiychuk, D.A. Frolov, M.D. Obushak, R.S. Stoika, A.M. Babsky // Вiopolymers and Cell. — 2017. — Т. 33, № 2. — С. 135-ХХ146 — Бібліогр.: 35 назв. — англ.

The development of novel efficient substances for anticancer chemotherapy is an important problem of medicinal chemistry. Aim. To evaluate the level of cytotoxic action of novel thiazole derivatives towards tumor cell lines of different origin. Methods. Four N acylated 2-amino-5-benzyl-1,3-thiazoles...