Buchumschlag

Antineoplastic activity of novel thiazole derivatives

The development of novel efficient substances for anticancer chemotherapy is an important problem of medicinal chemistry. Aim. To evaluate the level of cytotoxic action of novel thiazole derivatives towards tumor cell lines of different origin. Methods. Four N acylated 2-amino-5-benzyl-1,3-thiazoles...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Вiopolymers and Cell
Datum:	2017
Hauptverfasser:	Finiuk, N.S., Hreniuh, V.P., Ostapiuk, Yu.V., Matiychuk, V.S., Frolov, D.A., Obushak, M.D., Stoika, R.S., Babsky, A.M.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	Інститут молекулярної біології і генетики НАН України 2017
Schlagworte:	Bioorganic Chemistry
Online Zugang:	https://nasplib.isofts.kiev.ua/handle/123456789/152919
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:	Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:	Antineoplastic activity of novel thiazole derivatives / N.S. Finiuk, V.P. Hreniuh, Yu.V. Ostapiuk, V.S. Matiychuk, D.A. Frolov, M.D. Obushak, R.S. Stoika, A.M. Babsky // Вiopolymers and Cell. — 2017. — Т. 33, № 2. — С. 135-ХХ146 — Бібліогр.: 35 назв. — англ.

Institution

Digital Library of Periodicals of National Academy of Sciences of Ukraine

Ähnliche Einträge

Screening of spiro-substituted thiopyrano[2,3-d]thiazoles for their cytotoxic action on tumor cells
von: Zelisko, N.I., et al.
Veröffentlicht: (2017)

Synthesis and antitumor activities of new N-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides
von: Ostapiuk, Yu.V., et al.
Veröffentlicht: (2018)

Screening of antioxidant and anti-inflammatory activities among thiopyrano[2,3-d]thiazoles
von: Lozynskyi, A.V., et al.
Veröffentlicht: (2015)

Investigation of anticancer and anti-parasitic activity of thiopyrano[2,3-d]thiazoles bearing norbornane moiety
von: Kryshchyshyn, A.P., et al.
Veröffentlicht: (2017)

Computer-aided design of novel HIV-1 entry inhibitors blocking the virus envelope gp120 V3 loop
von: Andrianov, A.M., et al.
Veröffentlicht: (2012)

Use of lectins as vector molecules for delivery of drugs to cells and tissues. Report 2.
von: Antonyuk, V.O., et al.
Veröffentlicht: (2019)

DNA-binding studies of a series of novel water-soluble derivatives of 1,4-dihydropyridine
von: Leonova, E., et al.
Veröffentlicht: (2018)

Use of lectin as a vector molecule for delivery of medicinal products to cells and tissues
von: Antonyuk, V.O., et al.
Veröffentlicht: (2016)

Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2
von: Zinchenko, A.N., et al.
Veröffentlicht: (2017)

Increased antitumor efficiency and reduced negative side effects in laboratory mice of 4-thiazolidinone derivatives in complexes with PEG-containing polymeric nanocarrier
von: Kobylinska, L.I., et al.
Veröffentlicht: (2018)

Effect of inorganic nanoparticles and organic complexes on their basis on free-radical processes in some model systems
von: Averchenko, K.A., et al.
Veröffentlicht: (2015)

Genotoxicity of a carcinogenic metabolite of benzo[a]pyrene for cells of neuronal differentiation lineage
von: Endutkin, A.V., et al.
Veröffentlicht: (2012)

Lepidine Orange derivative as a new dye for sensitive fluorescent detection of DNA
von: Didan, Yu.V., et al.
Veröffentlicht: (2013)

Dynamics of dye release from nanocarriers of different types in model cell membranes and living cells
von: Tkacheva, T.N., et al.
Veröffentlicht: (2014)

Interaction of cationic porphyrin-imidazophenazine conjugates with DNA quadruplex: FID assay and quantum-chemical modeling
von: Didan, Yu.V., et al.
Veröffentlicht: (2018)

Structure–anticancer activity relationships among 4-azolidinone-3-carboxylic acids derivatives
von: Kaminskyy, D.V., et al.
Veröffentlicht: (2010)

Effects of oxyethylated glycerol cryoprotectants on phase transitions of DPPC model membranes
von: Kasian, N.A., et al.
Veröffentlicht: (2015)

Design of 4-(4-dialkylaminostyryl) -pyridinium dyes for fluorescent detection of amyloid fibrils
von: Inshyn, D.I., et al.
Veröffentlicht: (2016)

Inhibition of in vitro transcription by 2-arylidene derivatives of thiazolo[3,2-α]benzimidazol-3(2H)-one
von: Palchykovska, L.G., et al.
Veröffentlicht: (2010)

N-alkylaryl styrylcyanine dyes as fluorescent probes for nucleic acids detection
von: Kuperman, M.V., et al.
Veröffentlicht: (2018)

Ò7 Evaluation of antibacterial and antiviral activity of N-arylamides of 9-methyl- and 9-methoxyphenazine-1-carboxylic acids – inhibitors of the phage T7 model transctiption
von: Palchykovska, L.G., et al.
Veröffentlicht: (2012)

Anti-HIV activity of ellagitannins from alder tree fruits
von: Trokhymchuk, T.Yu., et al.
Veröffentlicht: (2018)

Hit identification of CK2 inhibitors by virtual screening
von: Protopopov, M.V., et al.
Veröffentlicht: (2017)

MI1 – derivative of maleimide inhibits cell cycle progression in tumor cells of epithelial origin
von: Garmanchuk, L.V., et al.
Veröffentlicht: (2013)

Effect of 24-epibrassinolide on lipoxygenase activity in maize seedlings under cold stress
von: Kopich, V.N., et al.
Veröffentlicht: (2010)

Hit identification of FGFR1 inhibitors using receptor-based virtual screening
von: Tarnavskiy, S.S., et al.
Veröffentlicht: (2019)

Synthesis and evaluation of antitumor activity of some thiazolo[4,5-b]pyridines
von: Chaban, T.I., et al.
Veröffentlicht: (2012)

Molecular complexes of the triterpene glycosides with L-tyrosine and their biological activity
von: Yakovishin, L.A., et al.
Veröffentlicht: (2012)

Spectroscopic study of binding of a cationic Pheophorbide-a to an antiparallel quadruplex Tel22
von: Ryazanova, O.A., et al.
Veröffentlicht: (2019)

Glycyrrhetinic acid and its derivatives as inhibitors of poly(ADP-ribose)polymerases 1 and 2, apurinic/apyrimidinic endonuclease 1 and DNA polymerase β
von: Zakharenko, A.L., et al.
Veröffentlicht: (2012)

Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors
von: Kotey, I.M., et al.
Veröffentlicht: (2019)

Toxic effect of C₆₀ fullerene-doxorubicin complex towards tumor and normal cells in vitro
von: Prylutska, S.V., et al.
Veröffentlicht: (2014)

Fluorine-containing polyamphiphiles of block structure constructed of synthetic and biopolymer blocks
von: Paiuk, O.L., et al.
Veröffentlicht: (2018)

Молекулярные комплексы тритерпеновых гликозидов с L-гистидином и их биологическая активность
von: Яковишин, Л.А., et al.
Veröffentlicht: (2011)

Synthesis and optical properties of lanthanides doped ultrasmall NaYF₄ markers for bio-medical applications
von: Podhorodecki, A., et al.
Veröffentlicht: (2011)

Спектрально-люминесцентные свойства производных скварилиевых зондов при взаимодействии с изолированными клетками печени крыс
von: Ткачева, Т.Н., et al.
Veröffentlicht: (2012)

Антивірусні властивості рослинних флавоноїдів – інгібіторів синтезу ДНК і РНК
von: Пальчиковська, Л.Г., et al.
Veröffentlicht: (2013)

Effects of thiazole derivatives on intracellular structure and functions in murine lymphoma cells
von: V. P. Hreniukh, et al.
Veröffentlicht: (2020)

Antineoplastic activity in vitro of 2-amino-5-benzylthiazole derivative in complex with nanoscale polymeric carriers
von: N. S. Finiuk, et al.
Veröffentlicht: (2021)

Study of antineoplastic action of novel isomeric derivatives of 4-thiazolidinone
von: V. V. Chumak, et al.
Veröffentlicht: (2014)