Cover Image

Antineoplastic activity of novel thiazole derivatives

The development of novel efficient substances for anticancer chemotherapy is an important problem of medicinal chemistry. Aim. To evaluate the level of cytotoxic action of novel thiazole derivatives towards tumor cell lines of different origin. Methods. Four N acylated 2-amino-5-benzyl-1,3-thiazoles...

Full description

Saved in:

Bibliographic Details
Published in:	Вiopolymers and Cell
Date:	2017
Main Authors:	Finiuk, N.S., Hreniuh, V.P., Ostapiuk, Yu.V., Matiychuk, V.S., Frolov, D.A., Obushak, M.D., Stoika, R.S., Babsky, A.M.
Format:	Article
Language:	English
Published:	Інститут молекулярної біології і генетики НАН України 2017
Subjects:	Bioorganic Chemistry
Online Access:	https://nasplib.isofts.kiev.ua/handle/123456789/152919
Tags:	Add Tag No Tags, Be the first to tag this record!
Journal Title:	Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:	Antineoplastic activity of novel thiazole derivatives / N.S. Finiuk, V.P. Hreniuh, Yu.V. Ostapiuk, V.S. Matiychuk, D.A. Frolov, M.D. Obushak, R.S. Stoika, A.M. Babsky // Вiopolymers and Cell. — 2017. — Т. 33, № 2. — С. 135-ХХ146 — Бібліогр.: 35 назв. — англ.

Institution

Digital Library of Periodicals of National Academy of Sciences of Ukraine

Similar Items

Screening of spiro-substituted thiopyrano[2,3-d]thiazoles for their cytotoxic action on tumor cells
by: Zelisko, N.I., et al.
Published: (2017)

Synthesis and antitumor activities of new N-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides
by: Ostapiuk, Yu.V., et al.
Published: (2018)

Screening of antioxidant and anti-inflammatory activities among thiopyrano[2,3-d]thiazoles
by: Lozynskyi, A.V., et al.
Published: (2015)

Investigation of anticancer and anti-parasitic activity of thiopyrano[2,3-d]thiazoles bearing norbornane moiety
by: Kryshchyshyn, A.P., et al.
Published: (2017)

Computer-aided design of novel HIV-1 entry inhibitors blocking the virus envelope gp120 V3 loop
by: Andrianov, A.M., et al.
Published: (2012)

Use of lectins as vector molecules for delivery of drugs to cells and tissues. Report 2.
by: Antonyuk, V.O., et al.
Published: (2019)

DNA-binding studies of a series of novel water-soluble derivatives of 1,4-dihydropyridine
by: Leonova, E., et al.
Published: (2018)

Use of lectin as a vector molecule for delivery of medicinal products to cells and tissues
by: Antonyuk, V.O., et al.
Published: (2016)

Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2
by: Zinchenko, A.N., et al.
Published: (2017)

Increased antitumor efficiency and reduced negative side effects in laboratory mice of 4-thiazolidinone derivatives in complexes with PEG-containing polymeric nanocarrier
by: Kobylinska, L.I., et al.
Published: (2018)

Effect of inorganic nanoparticles and organic complexes on their basis on free-radical processes in some model systems
by: Averchenko, K.A., et al.
Published: (2015)

Genotoxicity of a carcinogenic metabolite of benzo[a]pyrene for cells of neuronal differentiation lineage
by: Endutkin, A.V., et al.
Published: (2012)

Lepidine Orange derivative as a new dye for sensitive fluorescent detection of DNA
by: Didan, Yu.V., et al.
Published: (2013)

Dynamics of dye release from nanocarriers of different types in model cell membranes and living cells
by: Tkacheva, T.N., et al.
Published: (2014)

Interaction of cationic porphyrin-imidazophenazine conjugates with DNA quadruplex: FID assay and quantum-chemical modeling
by: Didan, Yu.V., et al.
Published: (2018)

Structure–anticancer activity relationships among 4-azolidinone-3-carboxylic acids derivatives
by: Kaminskyy, D.V., et al.
Published: (2010)

Effects of oxyethylated glycerol cryoprotectants on phase transitions of DPPC model membranes
by: Kasian, N.A., et al.
Published: (2015)

Design of 4-(4-dialkylaminostyryl) -pyridinium dyes for fluorescent detection of amyloid fibrils
by: Inshyn, D.I., et al.
Published: (2016)

Inhibition of in vitro transcription by 2-arylidene derivatives of thiazolo[3,2-α]benzimidazol-3(2H)-one
by: Palchykovska, L.G., et al.
Published: (2010)

N-alkylaryl styrylcyanine dyes as fluorescent probes for nucleic acids detection
by: Kuperman, M.V., et al.
Published: (2018)

Ò7 Evaluation of antibacterial and antiviral activity of N-arylamides of 9-methyl- and 9-methoxyphenazine-1-carboxylic acids – inhibitors of the phage T7 model transctiption
by: Palchykovska, L.G., et al.
Published: (2012)

Anti-HIV activity of ellagitannins from alder tree fruits
by: Trokhymchuk, T.Yu., et al.
Published: (2018)

Hit identification of CK2 inhibitors by virtual screening
by: Protopopov, M.V., et al.
Published: (2017)

MI1 – derivative of maleimide inhibits cell cycle progression in tumor cells of epithelial origin
by: Garmanchuk, L.V., et al.
Published: (2013)

Effect of 24-epibrassinolide on lipoxygenase activity in maize seedlings under cold stress
by: Kopich, V.N., et al.
Published: (2010)

Hit identification of FGFR1 inhibitors using receptor-based virtual screening
by: Tarnavskiy, S.S., et al.
Published: (2019)

Synthesis and evaluation of antitumor activity of some thiazolo[4,5-b]pyridines
by: Chaban, T.I., et al.
Published: (2012)

Molecular complexes of the triterpene glycosides with L-tyrosine and their biological activity
by: Yakovishin, L.A., et al.
Published: (2012)

Spectroscopic study of binding of a cationic Pheophorbide-a to an antiparallel quadruplex Tel22
by: Ryazanova, O.A., et al.
Published: (2019)

Glycyrrhetinic acid and its derivatives as inhibitors of poly(ADP-ribose)polymerases 1 and 2, apurinic/apyrimidinic endonuclease 1 and DNA polymerase β
by: Zakharenko, A.L., et al.
Published: (2012)

Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors
by: Kotey, I.M., et al.
Published: (2019)

Toxic effect of C₆₀ fullerene-doxorubicin complex towards tumor and normal cells in vitro
by: Prylutska, S.V., et al.
Published: (2014)

Fluorine-containing polyamphiphiles of block structure constructed of synthetic and biopolymer blocks
by: Paiuk, O.L., et al.
Published: (2018)

Молекулярные комплексы тритерпеновых гликозидов с L-гистидином и их биологическая активность
by: Яковишин, Л.А., et al.
Published: (2011)

Synthesis and optical properties of lanthanides doped ultrasmall NaYF₄ markers for bio-medical applications
by: Podhorodecki, A., et al.
Published: (2011)

Спектрально-люминесцентные свойства производных скварилиевых зондов при взаимодействии с изолированными клетками печени крыс
by: Ткачева, Т.Н., et al.
Published: (2012)

Антивірусні властивості рослинних флавоноїдів – інгібіторів синтезу ДНК і РНК
by: Пальчиковська, Л.Г., et al.
Published: (2013)

Effects of thiazole derivatives on intracellular structure and functions in murine lymphoma cells
by: V. P. Hreniukh, et al.
Published: (2020)

Antineoplastic activity in vitro of 2-amino-5-benzylthiazole derivative in complex with nanoscale polymeric carriers
by: N. S. Finiuk, et al.
Published: (2021)

Study of antineoplastic action of novel isomeric derivatives of 4-thiazolidinone
by: V. V. Chumak, et al.
Published: (2014)