Surface-exposed actin binds plasminogen on the membrane of agonist-activated platelets: a flow cytometry study

• Published in: Вiopolymers and Cell
• Date: 2017
• Main Authors: Tykhomyrov, A.A., Zhernossekov, D.D., Grinenko, T.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152928
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Surface-exposed actin binds plasminogen on the membrane of agonist-activated platelets: a flow cytometry study / A.A. Tykhomyrov, D.D. Zhernossekov, T.V. Grinenko // Вiopolymers and Cell. — 2017. — Т. 33, № 3. — С. 172-182. — Бібліогр.: 30 назв. — англ.

Aim. To elucidate whether actin exposed on the surface of agonist-activated platelets is responsible for plasminogen binding. Methods. Human washed platelets were obtained by gel-filtration on Sepharose-2B. The levels of exposed actin on the outer surface of plasma membrane of intact and thrombin- o...