Protein isoforms. Origin, structure and functions

• Published in: Вiopolymers and Cell
• Date: 2017
• Main Author: Novosylna, O.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2017
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152930
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Protein isoforms. Origin, structure and functions / O.V. Novosylna // Вiopolymers and Cell. — 2017. — Т. 33, № 3. — С. 161-171. — Бібліогр.: 79 назв. — англ.

Many proteins in mammalian organism exist as isoforms. These isoforms can be encoded by different genes or produced by alternative splicing of one gene. Despite rapid instrumental progress in the isoform identification, the reasons for their existence and specific functions remain largely unknown. D...