Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2
Aim. A search for human protein kinase CK2 inhibitors in a series of new amino-substituted pyrido[2,3-d]pyrimidine derivatives. Methods. Organic synthesis, analytical and spectral methods, molecular docking, in vitro biochemical testing. Results. Synthesis of new pyrido[2,3-d]pyrimidine derivatives...
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| Date: | 2017 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут молекулярної біології і генетики НАН України
2017
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| Series: | Вiopolymers and Cell |
| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/152990 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2 / A.N. Zinchenko, L.V. Muzychka, O.B. Smolii, V.G. Bdzhola, M.V. Protopopov, S.M. Yarmoluk // Вiopolymers and Cell. — 2017. — Т. 33, № 5. — С. 367-378. — Бібліогр.: 41 назв. — англ. |