Evolution of cell populations in vitro: peculiarities, driving forces, mechanisms and consequences

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2013
• 1. Verfasser: Kunakh, V.A.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2013
• Schlagworte: Reviews
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152992
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Evolution of cell populations in vitro: peculiarities, driving forces, mechanisms and consequences / V.A. Kunakh // Вiopolymers and Cell. — 2013. — Т. 29, №. 4. — С. 295-310. — Бібліогр.: 80 назв. — англ, укр.

This review outlines the major features and distinctions of cell populations, types and directions of selection in such populations. Population-genetic basis for cell adaptation to growth conditions in vitro is elucidated; in particular, peculiarities of genome evolution in the course of cell dediff...