Synthesis and study on biological activity of nitrogen-containing heterocyclic compounds – regulators of enzymes of nucleic acid biosynthesis

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Alexeeva, I.V., Shved, A.D.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152993
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Synthesis and study on biological activity of nitrogen-containing heterocyclic compounds – regulators of enzymes of nucleic acid biosynthesis / I.V. Alexeeva, A.D. Shved // Вiopolymers and Cell. — 2013. — Т. 29, №. 4. — С. 324-329. — Бібліогр.: 24 назв. — англ, укр.

Results of investigations on the development of new regulators of functional activity of nucleic acid biosynthesis enzymes based on polycyclic nitrogen-containing heterosystems are summarized. Computer design and molecular docking in the catalytic site of target enzyme (T7pol) allowed to perform the...