Rational design of protein kinase inhibitors

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Yarmoluk, S.M., Nyporko, A.Yu., Bdzhola, V.G.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152995
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Rational design of protein kinase inhibitors / S.M. Yarmoluk, A.Yu. Nyporko, V.G. Bdzhola // Вiopolymers and Cell. — 2013. — Т. 29, №. 4. — С. 339-347. — Бібліогр.: 44 назв. — англ.

Modern methodological approaches to rational design of low molecular weight compounds with specific activity in relation to predetermined biomolecular targets are considered by example of development of high effective protein kinase inhibitors. The application of new computational methods that allow...