Rational design of protein kinase inhibitors

• Datum: 2013
• Hauptverfasser: Yarmoluk, S.M., Nyporko, A.Yu., Bdzhola, V.G.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2013
• Schriftenreihe: Вiopolymers and Cell
• Schlagworte: Reviews
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/152995
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Rational design of protein kinase inhibitors / S.M. Yarmoluk, A.Yu. Nyporko, V.G. Bdzhola // Вiopolymers and Cell. — 2013. — Т. 29, №. 4. — С. 339-347. — Бібліогр.: 44 назв. — англ.

Modern methodological approaches to rational design of low molecular weight compounds with specific activity in relation to predetermined biomolecular targets are considered by example of development of high effective protein kinase inhibitors. The application of new computational methods that allow...