Development of the system for gene therapy of AIDS on the basis of antisense RNAs

• Published in: Вiopolymers and Cell
• Date: 2013
• Main Authors: Shved, A.D., Kukharenko, O.P.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2013
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/152999
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Development of the system for gene therapy of AIDS on the basis of antisense RNAs / A.D. Shved, O.P. Kukharenko // Вiopolymers and Cell. — 2013. — Т. 29, № 4. — С. 348-353. — Бібліогр.: 14 назв. — англ, укр.

Based on adeno-associated virus derived plasmid construct that are able to synthesize in cells antisense RNAs directed against key genes of HIV. Gematopoietic human cells carrying the created structure, acquired resistance to HIV infection, as evidenced by the reduction in infectious titer of HIV in...