Cardiospecific knockout of αE-catenin leads to violation of the neonatal cardiomyocytes maturation via β-catenin and Yap signaling

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2017
• Hauptverfasser: Balatskyi, V.V., Ruban, T.P., Macewicz, L.L., Piven, O.O.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2017
• Schlagworte: Genomics, Transcriptomics and Proteomics
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/153116
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Cardiospecific knockout of αE-catenin leads to violation of the neonatal cardiomyocytes maturation via β-catenin and Yap signaling / V.V. Balatskyi, T.P. Ruban, L.L. Macewicz, O.O. Piven // Вiopolymers and Cell. — 2017. — Т. 33, № 6. — С. 434-441. — Бібліогр.: 21 назв. — англ.

Aim. To study the αE-catenin gene function in neonatal cardiomyocytes proliferation and matura-tion. Methods. Conditional knockout approach, histological (H&E and acridine orange staining) and molecular genetics (qPCR) methods were used. Result. The hetero- and homozygous embry-onic cardiospecif...