Ku80 interaction with apurinic/apyrimidinic sites depends on the structure of DNA ends

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Kosova, A.A., Khodyreva, S.N., Lavrik, O.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153721
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Ku80 interaction with apurinic/apyrimidinic sites depends on the structure of DNA ends / A.A. Kosova, S.N. Khodyreva, O.I. Lavrik // Вiopolymers and Cell. — 2014. — Т. 30, № 1. — С. 42-46. — Бібліогр.: 10 назв. — англ.

Aim. The identification of a protein from human cell extract which specifically interacts with the apurinic/apyrimidinic (AP) site in the partial DNA duplex containing 5'and 3'-dangling ends (DDE-AP DNA) and mimicking clustered DNA damage. Methods. The Schiff base-dependent cross-linking o...