Suppression of tumorigenicity and metastatic potential of melanoma cells by transduction of interferon gene

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Lykhova, A.A., Kudryavets, Yu.I., Bezdenezhnykh, N.A., Semesiuk, N.I., Adamenko, I.N., Vorontsova, A.L.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Biomedicine
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153723
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Suppression of tumorigenicity and metastatic potential of melanoma cells by transduction of interferon gene / A.A. Lykhova, Yu.I. Kudryavets, N.A. Bezdenezhnykh, N.I. Semesiuk, I.N. Adamenko, A.L. Vorontsova // Вiopolymers and Cell. — 2014. — Т. 30, № 1. — С. 61-67. — Бібліогр.: 17 назв. — англ.

The aim of this study was to investigate an inhibitory effect of baculovirus-mediated transduction of the murine interferon-beta gene on mouse melanoma in vitro and in vivo. Methods. Studies were performed on B16 mouse melanoma (MM-4 cell line). Transduction, immunocytochemical and tumor cell biolog...