Growth suppression activity of bradykinin antagonists in glioma cells

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Avdieiev, S.S., Gera, L., Hodges, R., Vassetzky, Y.S., Kavsan, V.M.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Short Communications
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153733
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Growth suppression activity of bradykinin antagonists in glioma cells / S.S. Avdieiev, L. Gera, R. Hodges, Y.S. Vassetzky, V.M. Kavsan // Вiopolymers and Cell. — 2014. — Т. 30, № 1. — С. 77-79. — Бібліогр.: 7 назв. — англ.

The present study was Aimed at analyzing the effect of bradykinin (BK) antagonists on proliferation of the human glioblastoma cells U373. Methods. MTT-based cell proliferation assay. Results. BKM-570 revealed a significant antiproliferative activity in the U373 cells with LC50 3,8 M. Conclusions. Th...