Interaction of cyanine dyes with nucleic acids. I. Studies on monomethyne cyanine dyes as possible fluorescent probes for the detection of nucleic acids

• Published in: Биополимеры и клетка
• Date: 1996
• Main Authors: Yarmoluk, S.M., Zhyvoloup, A.N., Koval'ska, V.B., Klimenko, I.V., Kukharenko, A.P., Kovtun, Y.P., Slominsky, Y.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 1996
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153787
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Interaction of cyanine dyes with nucleic acids. I. Studies on monomethyne cyanine dyes as possible fluorescent probes for the detection of nucleic acids / S.M. Yarmoluk, A.N. Zhyvoloup, V.B. Koval'ska, I.V. Klimenko, A.P. Kukharenko, Y.P. Kovtun, Y.L. Slominsky // Биополимеры и клетка. — 1996. — Т. 12, № 1. — С. 69-74. — Бібліогр.: 7 назв. — англ.

The series of monomethyne cyanine dyes as possible fluorescent probes for DNA and RNA analysis were synthesized and their optical properties were studied. Two dyes interacted with native DNA and RNA with strong fluorescence enhancement (up to 350 and 1550 times for Cyan 3 and Cyan 6, respectively)....