Hydration change on complexation of aromatic ligands with DNA: molecular dynamics simulations

• Published in: Вiopolymers and Cell
• Date: 2010
• Main Authors: Kostjukov, V.V., Khomutova, N.M., Evstigneev, M.P.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2010
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/153856
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Hydration change on complexation of aromatic ligands with DNA: molecular dynamics simulations / V.V. Kostjukov, N.M. Khomutova, M.P. Evstigneev, // Вiopolymers and Cell. — 2010. — Т. 26, № 1. — С. 36-44. — Бібліогр.: 26 назв. — англ, рос.

Aim. Analysis of the hydration changes at formation of DNA complexes with biologically active aromatic compounds (BAC): antibiotics actinomycin D, daunomycin, nogalamycin, novantrone and mutagens ethidium bromide and proflavine. Methods. Molecular dynamics simulations. Results. The hydration indexes...