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Implementation of the quantitative Real-Time PCR for the molecular-genetic diagnostics of spinal muscular atrophy

Aim. To develop an easy and reliable assay for quantitative analysis of the SMN1 gene exon 7 copy number with Real-Time PCR and a SYBR Green dye which can be used as a test-system for spinal muscular atrophy (SMA) diagnostics. Methods. For the quantification the SMN1 gene exon 7 copies we have used...

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Bibliographic Details
Published in:Вiopolymers and Cell
Date:2010
Main Authors: Soloviov, O.O., Livshits, G.B., Podlesnaya, S.S., Livshits, L.A.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2010
Subjects:
Genomics, Transcriptomics and Proteomics
Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/153859
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Implementation of the quantitative Real-Time PCR for the molecular-genetic diagnostics of spinal muscular atrophy / O.O. Soloviov, G.B. Livshits, S.S. Podlesnaya, L.A. Livshits, // Вiopolymers and Cell. — 2010. — Т. 26, № 1. — С. 51-55. — Бібліогр.: 14 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine

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