Overexpression of adaptor protein Ruk/CIN85 in mouse breast adenocarcinoma 4T1 cells induces an increased migration rate and invasion potential

• Date: 2018
• Main Authors: Horak, I.R., Drobot, L.B., Borsig, L., Knopfova, L., Smarda, J.
• Format: Article
• Language: English
• Published: 2018
• Series: Інститут молекулярної біології і генетики НАН України
• Subjects: Structure and Function of Biopolymers
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154276
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Overexpression of adaptor protein Ruk/CIN85 in mouse breast adenocarcinoma 4T1 cells induces an increased migration rate and invasion potential / I.R. Horak, L.B. Drobot, L. Borsig, L. Knopfova, J. Smarda // Вiopolymers and Cell. — 2018. — Т. 34, № 4. — С. 284-291. — Бібліогр.: 33 назв. — англ.

Aim. To study the effect of adaptor protein Ruk/CIN85 overexpression on the dynamics of migration and Matrigel invasion as well as transendothelial migration of murine 4T1 breast adenocarcinoma cells. Methods. Dynamics of 4T1 cells migration/invasion was monitored in real time using the xCELLigence...