Model DNA for investigation of mechanism of nucleotide excision repair

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Evdokimov, A.N., Lavrik, O.I., Petruseva, I.O.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154301
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Model DNA for investigation of mechanism of nucleotide excision repair / A.N. Evdokimov, O.I. Lavrik, I.O. Petruseva // Вiopolymers and Cell. — 2014. — Т. 30, № 3. — С. 167-183. — Бібліогр.: 107 назв. — англ.

The living cell DNA is under permanent attack of a variety of exogenous and endogenous damaging factors. Nucleotide excision repair (NER) is main pathway which removes a wide variety of bulky DNA adducts formed by UV light, electrophilic environmental mutagens, and chemotherapeutic agents. NER proce...