Interaction of 2'-deoxyguanosine with cis-2-butene-1,4-dial: Computational approach to analysis of multistep chemical reactions

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Sviatenko, L.K., Gorb, L.G., Hovorun, D.M., Leszczynski, J.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Molecular Biophysics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154306
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Interaction of 2'-deoxyguanosine with cis-2-butene-1,4-dial: Computational approach to analysis of multistep chemical reactions / L.K. Sviatenko, L.G. Gorb, D.M. Hovorun, J. Leszczynski // Вiopolymers and Cell. — 2014. — Т. 30, № 3. — С. 239-246. — Бібліогр.: 10 назв. — англ.

cis-2-Butene-1,4-dial represents a microsomal metabolite of furan, an industrially important chemical found in cigarette smoke, air pollution, and also in canned or jarred food. It is expected to be a human carcinogen. Aim. Investigation an effect of cis-2-butene-1,4-dial on the 2'-deoxyguanine...