Study of SNRPN genetic and epigenetic mutations in Prader-Willi and Angelman patients

• Published in: Вiopolymers and Cell
• Date: 2018
• Main Authors: Chernushyn, S.Yu., Hryshchenko, N.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2018
• Subjects: Biomedicine
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154359
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Study of SNRPN genetic and epigenetic mutations in Prader-Willi and Angelman patients / S.Yu. Chernushyn, N.V. Hryshchenko // Вiopolymers and Cell. — 2018. — Т. 34, № 5. — С. 361-366. — Бібліогр.: 11 назв. — англ.

Prader-Willi (PWS) and Angelman (AS) syndromes are two clinically distinct genetic diseases associated with multiple physical and cognitive abnormalities. The genetic cause of PWS and AS is the alteration in the 15q11.2-q13 chromosomal region; expression of genes in this region is subject to genome...