Toxic effect of C₆₀ fullerene-doxorubicin complex towards tumor and normal cells in vitro

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Prylutska, S.V., Didenko, G.V., Potebnya, G.P., Bogutska, K.I., Prylutskyy, Yu.I., Ritter, U., Scharff, P.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Bioorganic Chemistry
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154553
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Toxic effect of C₆₀ fullerene-doxorubicin complex towards tumor and normal cells in vitro / S.V. Prylutska, G.V. Didenko, G.P. Potebnya, K.I. Bogutska, Yu.I. Prylutskyy, U. Ritter, P. Scharff // Вiopolymers and Cell. — 2014. — Т. 30, № 5. — С. 372-376. — Бібліогр.: 25 назв. — англ.

Creation of new nanostructures possessing high antitumor activity is an important problem of modern biotechnology. Aim. To evaluate cytotoxicity of created complex of pristine C₆₀ fullerene with the anthracycline antibiotic doxorubicin (Dox), as well as of free C₆₀ fullerene and Dox, towards differe...