Nucleosomal packaging of eukaryotic DNA and regulation of transcription

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Golov, A.K., Razin, S.V., Gavrilov, A.A.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154580
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Nucleosomal packaging of eukaryotic DNA and regulation of transcription / A.K. Golov, S.V. Razin, A.A. Gavrilov // Вiopolymers and Cell. — 2014. — Т. 30, № 6. — С. 413-425. — Бібліогр.: 211 назв. — англ.

The eukaryotic nucleus harbors genomic DNA, which is tens of thousands of times greater in linear size than the nuclear diameter. Its high condensation is due to DNA packaging in chromatin, and DNA wrapping around nucleosomal globules is a key step in the process. A histone octamer, which forms the...