Influence of EMAP II, IFN-α2b and its medicinal preparations on the MGMT protein amount in human cells in vitro

• Published in: Вiopolymers and Cell
• Date: 2014
• Main Authors: Kotsarenko, K.V., Lylo, V.V., Ruban, T.P., Macewicz, L.L., Kornelyuk, A.I., Chernykh, S.I., Lukash, L.L.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2014
• Subjects: Genomics, Transcriptomics and Proteomics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/154591
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Influence of EMAP II, IFN-α2b and its medicinal preparations on the MGMT protein amount in human cells in vitro / K.V. Kotsarenko, V.V. Lylo, T.P. Ruban, L.L. Macewicz, A.I. Kornelyuk, S.I. Chernykh, L.L. Lukash // Вiopolymers and Cell. — 2014. — Т. 30, № 6. — С. 448-453. — Бібліогр.: 31 назв. — англ.

Aim. To study the effect of EMAP II, IFN-α2b and its medicinal preparations on the amount of O6-methylguanine-DNA methyltransferase (MGMT) protein in human cells in vitro. Methods. The human cells of 4BL and Hep-2 lines were treated with the purified recombinant proteins EMAP II, IFN-α2b and its com...