Ca²⁺ does not affect the binding properties of ITSN1 EH domains

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2014
• Hauptverfasser: Morderer, D.Ye., Rymarenko, O.V., Skrypkina, I.Ya., Rynditch, A.V.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2014
• Schlagworte: Short Communications
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/154596
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Ca²⁺ does not affect the binding properties of ITSN1 EH domains / D.Ye. Morderer, O.V. Rymarenko, I.Ya. Skrypkina, A.V. Rynditch // Вiopolymers and Cell. — 2014. — Т. 30, № 6. — С. 481-484. — Бібліогр.: 16 назв. — англ.

ITSN1 is an endocytic scaffold protein implicated in synaptic functioning. Ca²⁺ is known to be important for endo- cytosis in both pre- and post-synaptic terminals. ITSN1 contains two EH (Eps15 homology) domains which possess putative Ca²⁺-binding EF-hand motifs. Aim. To test the effect of Ca²⁺ on t...