Synthesis and use of disulfide-based H-phosphonate reagent for 3'- and/or 5'-oligonucleotide labelling via mercaptoalkyl linke

• Veröffentlicht in: Биополимеры и клетка
• Datum: 1998
• Hauptverfasser: Dubey, I.Y., Fedoryak, D.M.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 1998
• Schlagworte: Методы
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/154992
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Synthesis and use of disulfide-based H-phosphonate reagent for 3'- and/or 5'-oligonucleotide labelling via mercaptoalkyl linke / I.Y. Dubey, D M. Fedoryak // Биополимеры и клетка. — 1998. — Т. 14, № 2. — С. 163-172. — Бібліогр.: 43 назв. — англ.

Synthesis of new disulfide-based H-phosphonate reagent for solid-phase oligonucleotide functionalization with mercaptopropyl group at one or two termini is described. Using this single reagent, 3'- and 3', 5'-disulfide-linked oligonucleotides were synthesized', disulfide bonds cl...