Among Escherichia coli Genetic Stock Center strains many are resistant to cytotoxic antimetabolites

• Published in: Біополімери і клітина
• Date: 2002
• Main Authors: Cherepenko, E.I., Karpenko, O.I.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2002
• Subjects: Короткі повідомлення
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/155984
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Among Escherichia coli Genetic Stock Center strains many are resistant to cytotoxic antimetabolites / E.I. Cherepenko, O.I. Karpenko // Вiopolymers and Cell. — 2002. — Т. 18, № 3. — С. 
 253-254. — Бібліогр.: 5 назв. — англ.

Mutants resistant to cytotoxic antimetabolites arise in E. coli with a frequency about 10⁻⁴. Because most in this collection strains contacted a mutagen we checked how many strains could tolerate two inhibitors used: glyphosate and 6-aza-uracil. Among 28 strains studied 12 could tolerate these inhib...