Synthesis and characterization of fluorogenic peptide substrate of HIV-1 protease based on fluorescence resonance energy transfer

• Published in: Биополимеры и клетка
• Date: 1995
• Main Authors: Kornelyuk, A.I., Terentiev, A.G., Fisher, S., Porter, T.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 1995
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156188
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Synthesis and characterization of fluorogenic peptide substrate of HIV-1 protease based on fluorescence resonance energy transfer / A.L. Kornelyuk, A.G. Terentiev, S. Fisher, T. Porter // Биополимеры и клетка. — 1995. — Т. 11, № 6. — С. 57-61. — Бібліогр.: 18 назв. — англ.

Synthesis of fluorogenic peptide substrate of HIV-I protease Dns-SQNYPIVWL which corresponds to the p17/p24 cleavage site for HIV-l protease have been performed. This fluorogenic substrate was based on the fluorescence resonance energy transfer between donor – Trp residue, and acceptor – dansyl grou...