The hepatitis В virus: general description, physical structure, genetic organization, gene transcripts and genomic regulatory elements

• Published in: Биополимеры и клетка
• Date: 1999
• Main Author: Adjamian, F.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 1999
• Subjects: Обзоры
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156323
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: The hepatitis В virus: general description, physical structure, genetic organization, gene transcripts and genomic regulatory elements / F. Adjamian // Биополимеры и клетка. — 1999. — Т. 15, № 2. — С. 109-121. — Бібліогр.: 156 назв. — англ.

The HBV genome is a circular partially double-stranded DNA molecule. It contains four overlapping open reading frames (ORFs) genes. The S (preS1, preS2) region(s) encodes the major (small), middle and large proteins (HBsAg). The C and pre-C regions encode HBcAg and HBeAg. The X region encodes a poly...