Cytokine activity of the non-catalytic EMAP-2-like domain of mammalian tyrosyl-tRNA synthetase

• Published in: Биополимеры и клетка
• Date: 1999
• Main Authors: Kornelyuk, A., Tas, M., Dubrovsky, A., Murray, J.C.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 1999
• Subjects: Приоритетные работы
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156329
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Cytokine activity of the non-catalytic EMAP-2-like domain of mammalian tyrosyl-tRNA synthetase / A. Kornelyuk, M. Tas, A. Dubrovsky, J.C. Murray // Биополимеры и клетка. — 1999. — Т. 15, № 2. — С. 168-172. — Бібліогр.: 23 назв. — англ.

Cytokine activity of the isolated recombinant C-terminal domain of mammalian lyrosyl-tRNA synthetasg (TyrRS), which is homologous to a tumor-derived cytokine, endothelial and monocyte activating polypeptide (EMAP-2) has been studied. It was shown that C-domain induced a ~ 2-fold increase of monocyte...