Interaction of PARP2 with DNA structures mimicking DNA repair intermediates

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2011
• Hauptverfasser: Kutuzov, M.M., Ame, J.-C., Khodyreva, S.N., Schreiber, V., Lavrik, O.I.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2011
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/156332
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Interaction of PARP2 with DNA structures mimicking DNA repair intermediates / M.M. Kutuzov, J.-C. Ame, S.N. Khodyreva, V. Schreiber, O.I. Lavrik // Вiopolymers and Cell. — 2011. — Т. 27, № 5. — С. 383-386. — Бібліогр.: 5 назв. — англ.

Poly(ADP-ribosyl)ation is a posttranslational protein modification significant for the genomic stability and cell survival in response to DNA damage. Poly(ADP-ribosyl)ation is catalyzed by poly(ADP-ribose)polymerases (PARPs). Whereas the role of PARP1 in response to DNA damage has been widely illu...