Characterization and vectorization of siRNA targeting RET/PTC1 in human papillary thyroid carcinoma cells

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2011
• ISSN: 0233-7657
• 1. Verfasser: Massade, L.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2011
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/156380
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Characterization and vectorization of siRNA targeting RET/PTC1 in human papillary thyroid carcinoma cells / L.Massade // Вiopolymers and Cell. — 2011. — Т. 27, № 5. — С. 390-393. — Бібліогр.: 20 назв. — англ.

RET/PTC1 fusion oncogene is the most common genetic alteration identified to date in thyroid papillary
 carcinomas (PTC) and represents a good target forsmall interfering RNA (siRNA). Our aim was: i) to target the
 RET/PTC1 oncogene by siRNAs, ii) to assess the knockdown effects on c...