Association of mitochondrial lysyl-tRNA synthetase with HIV-1 GagPol involves catalytic domain of the synthetase and transframe and integrase domains of Pol

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2011
• Hauptverfasser: Kobbi, L., Dias, J., Octobre, G., Comisso, M., Kaminska, M., Shalak, V.F., Mirande, M.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2011
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/156406
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Association of mitochondrial lysyl-tRNA synthetase with
 HIV-1 GagPol involves catalytic domain of the synthetase
 and transframe and integrase domains of Pol
 / L. Kobbi, J. Dias, G. Octobre, M. Comisso, M. Kaminska, V.F. Shalak, M. Mirande
 // Вiopolymers and Cell. — 2011. — Т. 27, № 5. — С. 381-382. — Бібліогр.: 8 назв. — англ.

Aim. Analyze the interaction between Lysyl-tRNA synthetase (LysRS) and HIV-1 GagPol to know whether a particular N-terminal sequence of mitochondrial LysRS triggers a specific recognition with GagPol. Methods.
 Yeast two-hybrid analysis, immunoprecipitation. Results. We have shown that LysR...