Synthesis of model DNA and their application as substrates of nucleotide excision repair

• Veröffentlicht in: Вiopolymers and Cell
• Datum: 2012
• Hauptverfasser: Evdokimov, A.N., Tsidulko, A.Yu., Petruseva, I.O., Koroleva, L.S., Serpokrylova, I.Yu., Silnikov, V.N., Lavrik, O.I.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2012
• Schlagworte: Structure and Function of Biopolymers
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/156845
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Synthesis of model DNA and their application as substrates of nucleotide excision repair / A.N. Evdokimov, A.Yu. Tsidulko, I.O. Petruseva, L.S. Koroleva, I.Yu. Serpokrylova, V.N. Silnikov, O.I. Lavrik // Вiopolymers and Cell. — 2012. — Т. 28, № 3. — С. 212–217. — Бібліогр.: 20 назв. — англ.

Aim. Nucleotide excision repair (NER) is DNA repair system responsible to remove bulky lesions from DNA. These lesions appear in DNA as consequence of UV-light irradiation or environmental stress. Study of NER is extremely important to improve action of chemotherapeutic drugs. Methods. In vitro NER-...