PTI-1: novel way to oncogenicity

• Published in: Вiopolymers and Cell
• Date: 2012
• Main Authors: Vislovukh, A.A., Shalak, V.F., Savytskyi, O.V., Kovalenko, N.I., Gralievska, N.L., Negrutskii, B.S., El’skaya, A.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2012
• Subjects: Bioinformatics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/156941
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: PTI-1: novel way to oncogenicity / A.A. Vislovukh, V.F. Shalak, O.V. Savytskyi, N.I. Kovalenko, N.L. Gralievska, B.S. Negrutskii, A.V. El’skaya // Вiopolymers and Cell. — 2012. — Т. 28, № 5. — С. 404-410. — Бібліогр.: 47 назв. — англ.

Aim. The prostate tumor-inducing oncogene (PTI-1), presumably encoding a truncated form of eukaryotic translation elongation factor 1A1 (eEF1A1), was discovered as a gene overexpressed in prostate tumor samples and absent in normal tissues. The mechanism of PTI-1 oncogenicity remains obscure. Method...